Skin Tightening & Elasticity Revival
Rapid weight loss often leads to loose, sagging skin and a noticeable loss of elasticity. To address this common concern, Luxarise® is specially formulated with NAD+ and collagen-boosting factors to help restore skin firmness and thickness.
These key ingredients stimulate the production of collagen and elastin, effectively tightening the skin, smoothing fine lines, and reducing sagging—bringing back a youthful, healthy glow. This means you can not only achieve successful fat loss and body shaping, but also maintain a firm, youthful appearance, avoiding the “thin but older-looking” effect and allowing slimming and skin rejuvenation to happen at the same time.
In addition, the formula is enriched with a range of powerful anti-aging and skin-firming compounds. Green Tea Extract, Curcumin, and Moringa provide potent antioxidant and anti-inflammatory protection, while collagen helps repair the skin, deeply hydrate it, and improve overall skin condition. This advanced synergistic blend not only delivers anti-wrinkle and anti-aging benefits, but also supports the recovery of skin laxity after weight loss—restoring firmness, elasticity, and resilience.
Clinical results show that in as little as 4 weeks, over 82% of users experienced improved hydration, smoother fine lines, firmer skin, and a visibly lifted appearance—regaining a youthful, sculpted look even after significant weight loss.
Cardiovascular Health
Berberine enhances vasodilation by promoting nitric oxide production in vascular endothelial cells through increased SIRT1 activation. Moringa, quercetin, and berberine synergistically act on inflammatory and lipid metabolic pathways to promote fat metabolism and reduce visceral fat accumulation. This multi-pathway synergy helps maintain younger, more resilient blood vessels, optimize hemodynamics, balance lipid profiles, and enhance overall cardiovascular resilience.
Blood Sugar Balance
Moringa and Berberine slow the absorption of carbohydrates, reduce post-meal blood sugar spikes, and optimize hepatic glycogen storage and fat metabolism efficiency. With continued use, participants experienced significant reductions in fasting blood glucose and HbA1c, improved energy utilization, and more stable blood glucose curves throughout the day. Insulin responsiveness was markedly enhanced, metabolic rate increased, and the synergistic effects of the compound resulted in lower blood sugar peaks, tighter blood glucose control, faster recovery, and overall more.
Liver Support
Curcumin enhances the activity of Phase I and Phase II hepatic detoxification enzymes, accelerates fatty acid oxidation, and increases mitochondrial energy output. Berberine further improves hepatic detoxification efficiency, significantly reduces lipid accumulation, and stabilizes mitochondrial function. Together, this synergistic interaction promotes more robust metabolic cleansing capacity, lowers inflammatory activity, and helps maintain a healthier liver state. With continued use, this synergy not only supports improvements in liver enzyme markers, cholesterol balance, and insulin resistance, but also contributes to the restoration of optimal liver function, metabolic efficiency, and the body’s natural detoxification capacity.
Inflammation & Oxidative Stress Reduction
Curcumin anti-inflammatory activity helps improve soft-tissue flexibility, reduce joint swelling, protect cartilage and bone density, and relax tense muscles—effectively interrupting the cycle of chronic systemic inflammation that often worsens joint discomfort. Studies show that this nutrient combination provides both immediate soothing relief and long-term structural support, helping prevent joint degeneration and bone loss. In user experience studies, up to 96.65% of participants reported a significant reduction in joint pain within just two weeks, along with improved mobility and daily comfort.
Gut Health
Apple cider vinegar powder, white kidney bean extract work synergistically on carbohydrate metabolism and gut motility by reducing digestive enzyme activity and supporting hepatic and biliary detoxification and bile flow—promoting fat digestion, nutrient absorption, and endotoxin clearance to maintain a more balanced intestinal environment. Moringa, green tea extract, rich in natural polyphenols, help inhibit pathogenic bacteria, support the expansion of beneficial probiotics, and enhance microbiome diversity, improving bloating, irregular bowel movements, and overall digestive discomfort.
Mood and Energy Regulation & Brain Protection
With aging, increased stress, and a fast-paced lifestyle, many people experience mood swings, anxiety, insomnia, memory decline, and brain fog due to blood sugar fluctuations, elevated inflammation, low energy levels, and nervous system overload. For women, menopause can further intensify symptoms such as hot flashes, emotional instability, and poor sleep quality.
To address these challenges, key ingredients work synergistically: curcumin helps reduce stress-related responses and supports better sleep; moringa helps protect neurons and enhance focus; and NAD⁺/NMN support the restoration of brain energy.
Clinical data show that within 2–4 weeks, over 85% of users experienced improvements in mood and sleep; within 4–6 weeks, approximately 80% reported better memory and reduced brain fog; and more than 79% of women reported noticeable relief from menopause-related symptoms. Overall, this combination helps stabilize mood, restore cognitive performance, and keep the mind clear, focused, and energized.
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® & 10–1 : Transforming Weight, Liver, Gut & Skin Health
In clinical studies, users taking ® & 10–1 achieved breakthrough results—some dropping 6-8 pounds of stubborn fat in just one week. Once daily dose targets the most resistant visceral and abdominal fat, sculpting a leaner physique without grueling high-intensity workouts. This isn’t just weight loss—it’s precision fat elimination that reshapes your body from the inside out. The data speaks for itself: real users, real results, zero crash dieting required.
Endocrinology Team’s Top Recommendation
“We are a professional team with extensive clinical and research experience in the field of endocrinology, and many of our members have personally experienced obesity and its related complications. We have also tried a wide range of common weight-loss products available on the market, often with very limited results. These firsthand experiences motivated us to develop a solution for metabolic health and weight management that is safe, natural, and truly effective. After 12 years of continuous research, our team first conducted self-testing and successfully broke through the limitations of traditional single-pathway mechanisms. By utilizing a dual-pathway approach, we achieved significant improvements in weight reduction and metabolic health, with no rebound effects and no adverse reactions. We then conducted large-scale studies and clinical trials involving more than 5,000 participants, which further validated the performance of ® & 10–1 in metabolic regulation, appetite control, and overall wellness—showing especially strong results among adults over 40 with overweight or obesity. Supported by contemporary medical research, ® & 10–1 has passed the ISO9001’s rigorous regulatory review and certification, with its safety, effectiveness, and compliance formally recognized. It represents a scientific advancement beyond traditional solutions, offering a natural, safe, and effective option for individuals seeking comprehensive metabolic support and long-term weight management.”
✅ Made in aGMP-certified facility
✅ ISO9001-compliant natural ingredients
✅ Effective forall ages
✅ Visible results in just 7 Days
✅ Supportslong-term weight controland disease prevention
100% Natural Ingredients, Compatible with Other Medications
This 100% natural, scientifically formulated patch is designed so that all active ingredients work synergistically without interference. Because it bypasses the digestive system, it can be safely used alongside daily meals and routine products. The patch is vegan-friendly, offers high transdermal absorption, and contains no hormones, sugars, or allergenic ingredients. It is non-GMO, gluten-free, soy-free, and free from artificial colors, fragrances, and preservatives.
Using advanced transdermal delivery technology, the active compounds are released slowly and steadily through the skin barrier, entering the microcirculation and targeting specific areas for precise, sustained, and gentle support. Safe, reliable, and cruelty-free, the patch is suitable for all skin types and body types. It has been verified through relevant testing, with noticeable improvements felt in as little as 7 days.

Moringa :Demonstrates significant blood sugar control effects by enhancing insulin sensitivity to help lower blood glucose levels. Its antioxidant components reduce oxidative stress, thereby alleviating inflammation triggered by diabetes. Additionally, moringa improves liver function and promotes fat metabolism. These combined factors contribute to maintaining stable blood sugar levels, aiding in the prevention and management of diabetes.
White Kidney Bean Extract:Rich in amylase inhibitors, it reduces the digestion and absorption of carbohydrates, aiding in weight management and minimizing fat accumulation. It also possesses antioxidant properties that help neutralize free radicals, alleviate oxidative stress on liver cells, support normal liver metabolism and detoxification functions, and promote overall liver health.
❤️ Green Tea Extract:Rich in antioxidants such as catechins, particularly EGCG (epigallocatechin gallate). It possesses potent antioxidant and anti-inflammatory properties, promoting fat burning, boosting metabolism, supporting cardiovascular health, enhancing brain function, and exhibiting potential anti-cancer effects.
Quercetin:It plays a significant role in joint health and inflammation regulation, primarily due to its potent antioxidant, anti-inflammatory, anti-allergic, and antiviral properties. It inhibits the release of multiple inflammatory mediators, alleviating joint swelling, pain, and stiffness, making it particularly suitable for individuals with arthritis and chronic inflammation. It also improves cardiovascular health, reduces allergy symptoms, and strengthens the immune system.
NAD+:It is an intracellular coenzyme essential for energy production. It helps boost cellular metabolism, slow aging, repair DNA damage, improve heart health and cognitive function, and may increase lifespan.
✨Curcumin:Curcumin is the primary active ingredient in turmeric, boasting potent anti-inflammatory, antioxidant, and anti-cancer properties. It helps alleviate joint inflammation, improve digestive health, protect heart health, reduce stress and anxiety, and exhibits anti-cancer effects.
⚡ Collagen Peptides:It is a hydrolyzed form of collagen that helps enhance skin elasticity, reduce wrinkles and fine lines, improve bone health, increase muscle mass, and promote joint health. It also improves hair and nail health and supports intestinal repair.
Apple Cider Vinegar Powder:Rich in organic acids, particularly acetic acid, it promotes digestion, regulates blood sugar and cholesterol levels, and aids in weight loss. It also possesses antibacterial properties, helps improve skin health, alleviates gastrointestinal discomfort, and enhances the liver’s detoxification function.
Check out more of our customers’ satisfaction feedback!
“Ten years of nursing destroyed my health. Crazy shifts meant skipping meals for 8 hours, then coming home exhausted and binge-eating everything in sight. My weight shot from 160 to 287 pounds—my scrubs barely fit, and I nearly passed out from low blood sugar during a shift. My doctor said I was pre-diabetic. A coworker mentioned ® & 10–1 , and honestly, I didn’t expect much. But within two weeks, my appetite crashed. No more sugar cravings, and after night shifts, I wasn’t ravenous anymore.
By month two, my energy was back. Started evening walks again. Four months later—170 pounds gone, down to 117. My skin didn’t get all saggy and loose like you’d expect from such rapid weight loss. I’m actually pretty satisfied with how tight everything stayed. I’m still nursing, but now I take care of myself too. I tell my patients struggling with weight: it’s never too late to get your health back.” — Sarah Thompson

About 62 days ago, I started ® & 10–1 . At first, I was skeptical—but it was worth a try.
First 2 weeks: I noticed the inflammation and swelling slowly going down, and the dizzy spells became much less frequent.
30 days: I was able to keep up with housework again and even do some gardening. My energy was gradually coming back.
Day 45: I could easily walk to the corner store without needing to stop and rest. My blood sugar was more stable, and I no longer felt that heavy crash after meals.
Day 62: Unbelievable! I can now walk on the treadmill for 40 minutes straight (keeping my heart rate in Zone 2), and even do light stretching and weights at the gym. Just a few days ago, I rebuilt the fence in our backyard—measuring, sawing, drilling, and carrying wood, working for seven hours! Yes, I was tired, but it was the good kind of tired, not the weak, sickly exhaustion I used to feel.
Now, I’d say I’ve regained at least 80% of my energy. I can play ball with my grandkids again, and I’m even planning to get back on the tennis court. Honestly, I don’t know if it’s just the ® & 10–1 itself, or the combination of the formula with my new exercise routine—but one thing is certain: since I started ®, I’ve gotten my life back.—Emily Johnson

® & 10–1 turned everything around. Week two, sleeping through the night again, no more 3 AM anxiety spirals. Mental fog lifted—I could actually keep up with lesson plans and remember where each class left off. Three months later, blood pressure dropped to 125/78, lost 45 pounds. But the real game-changer was getting my brain back. Energy’s through the roof, classroom management is smooth again. Kids actually said I seem like a different person.”—Olivia Martin
Why ® & 10–1 is Your Best Choice?
✅ Additional Benefits: Can address multiple obesity-related complications, such as cardiovascular disease, type 2 diabetes, arthritis, high obesity/hypertension, fatty liver, liver function recovery, brain fog and memory decline, as well as women’s health issues including hormonal imbalances, menopause-related symptoms, and vaginal problems such as itching and odor.
✅Transdermal Microneedling Technology:Breaking away from traditional injection or oral weight management methods, the nano-microneedle transdermal delivery system provides sustained release of active ingredients for up to 8 hours. Moringa and berberine synergistically support appetite regulation and fat metabolism, making fat reduction more natural and effortless; NAD⁺ maintains energy levels and skin firmness. The gentle, stable formulation delivers a comfortable, non-irritating weight management experience.
✅ All Body Types: Regardless of your body type, it is suitable for everyone, including moderate situations.
✅ Efficient Transdermal Absorption: The patch utilizes transdermal absorption technology, allowing active ingredients to bypass the gastrointestinal system and enter the microcirculation through the skin to exert their effects. This approach is gentler on the stomach and intestines, making it particularly suitable for individuals with sensitive digestive systems.
✅ Trusted Brand: ® is a trusted brand known for providing high-quality weight management products that are research-supported and have earned customer satisfaction.
✅ Safe and Effective: Our advanced nano microneedle patch is made with natural ingredients and a science-based formulation, and is manufactured in ISO9001-compliant, GMP-certified facilities to ensure quality and safety.
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Natalie Parker –
Simple drops that support immunity plus digestion daily.
Matthew Brooks –
Heart health support feels reassuring plus daily vitality.
Chloe Anderson –
Fast absorbing formula with antioxidant support plus comfort.
Ryan Mitchell –
Energy stays balanced plus digestion feels calm.
Emma Foster –
Feels gentle yet effective with immunity lift plus clarity.
James Coleman –
Great support for digestion plus overall wellness boost.
Olivia Harris –
Daily energy feels more stable plus body feels lighter.
Daniel Wright –
Easy drops with smooth digestion plus heart support feeling.
Sophia Bennett –
Immunity feels stronger plus antioxidant support is noticeable.
Michael Turner –
Fast absorption gives clean energy plus better digestion throughout the day.
Tyler Prescott –
Nano delivery provides consistent results for body balance plus skin tone.
Jordan Whitaker –
Daily use promotes steady energy metabolic support with a lightweight feel.
Caleb Monroe –
This microneedle patch supports weight management metabolism energy balance skin firmness.